StoppingTargetProb-class {crmPack}

Stop based on probability of target tox interval

Description

Stop based on probability of target tox interval

Slots

target

the target toxicity interval, e.g. c(0.2, 0.35)

prob

required target toxicity probability (e.g. 0.4) for reaching sufficient precision

Examples

# As example, here is the rule for: 
#   stopping the study if the posterior probability that [0.2 =< Prob(DLT | dose) <= 0.35] 
#   for the next best dose is above 0.5

myStopping <- StoppingTargetProb(target=c(0.2, 0.35),
                                 prob=0.5)