StoppingTDCIRatio-class {crmPack}

Stop based on a target ratio, the ratio of the upper to the lower 95% credibility interval of the estimate of TD end of trial, the dose with probability of DLE equals to the target probability of DLE used at the end of a trial

Description

Stop based on a target ratio, the ratio of the upper to the lower 95% credibility interval of the estimate of TD end of trial, the dose with probability of DLE equals to the target probability of DLE used at the end of a trial

Slots

targetRatio

the target ratio of the upper to the lower of the 95% credibility interval of the estimate that required to stop a trial

targetEndOfTrial

the target probability of DLE to be used at the end of a trial

Examples

##Define the target stopping ratio of 5 and 
##the target probability of DLE to be used at the end of a trial
##This is a ratio of the upper to the lower 95% credibility interval of the estimates
myStopping <- StoppingTDCIRatio(targetRatio=5,
                                targetEndOfTrial=0.3)