CohortSizeMin-class {crmPack} | R Documentation |
Size based on minimum of multiple cohort size rules
Description
This class can be used to combine multiple cohort size rules with the MIN operation.
Details
cohortSizeList
contains all cohort size rules, which are again
objects of class CohortSize
. The minimum of these
individual cohort sizes is taken to give the final cohort size.
Slots
cohortSizeList
list of cohort size rules
Examples
# Rule for having cohort of size 1 for doses <30
# and having cohort of size 3 for doses >=30
mySize1 <- CohortSizeRange(intervals = c(0, 10),
cohortSize = c(1, 3))
# Rule for having cohort of size 1 until no DLT were observed
# and having cohort of size 3 as soon as 1 DLT is observed
mySize2 <- CohortSizeDLT(DLTintervals=c(0, 1),
cohortSize=c(1, 3))
# Create a list of cohort size rules of class 'CohortSizeMax' which will then be
# combined with the 'min' operation
mySize <- CohortSizeMin(cohortSizeList=list(mySize1,
mySize2))
[Package crmPack version 1.0.6 Index]