coxrt {coxrt} | R Documentation |
The method assumes that truncation is independent of covariates, and of lifetime, and that there is no censoring. The method uses Inverse-Probability-Weighting estimating equations with stabilized weights, IPW-S and IPW-SA, as described in Vakulenko-Lagun et al. (2018). Currently the code allows only time-independent covariates.
The coxrt package provides two functions:
coxph.RT
(IPW-S) that assumes positivity
and coxph.RT.a0
(IPW-SA) that allows
for adjustment of estimation using plugged-in a0
.
The illustrative examples in these functions include analysis of AIDS
latency data with age as a covariate, where the AIDS cases were retrospectively
ascertained at June 30, 1986, and only those who developed AIDS by that time were
included in the analysis (Kalbfeisch and Lawless, 1989).
Vakulenko-Lagun, B., Mandel, M., Betensky, R.A. Inverse probability weighting methods for Cox regression with right-truncated data. 2019, submitted to Biometrics
Kalbfeisch, J.D. and Lawless, J.F. Inference based on retrospective ascertainment: an analysis of the data on transfusion-related AIDS. Journal of the American Statistical Association, 84 (406):360-372, 1989.