Title: Mixed Effects Cox Models Priority: optional Package: coxme Version: 2.2-20 Depends: survival (>= 2.36.14), methods, bdsmatrix(>= 1.3), R(>= 2.10) Imports: nlme, Matrix (>= 1.0) Suggests: mvtnorm, kinship2 LinkingTo: bdsmatrix LazyData: Yes LazyLoad: Yes Authors@R: person(c("Terry", "M."), "Therneau", role=c("aut", "cre"), email="therneau.terry@mayo.edu") Description: Fit Cox proportional hazards models containing both fixed and random effects. The random effects can have a general form, of which familial interactions (a "kinship" matrix) is a particular special case. Note that the simplest case of a mixed effects Cox model, i.e. a single random per-group intercept, is also called a "frailty" model. The approach is based on Ripatti and Palmgren, Biometrics 2002. License: LGPL-2 NeedsCompilation: yes Packaged: 2024-03-04 19:55:10 UTC; therneau Author: Terry M. Therneau [aut, cre] Maintainer: Terry M. Therneau Repository: CRAN Date/Publication: 2024-03-05 05:30:39 UTC