Experimental_Properties_Drug {covid19dbcand}

Drug Experimental Properties

Description

Drug properties that have been experimentally proven. Each drug may have one or more experimental property.

Usage

Experimental_Properties_Drug

Format

a tibble with 4 variables:

kind

Name of the property

value

Drug properties that have been experimentally proven

source

Reference to the source of this experimental data

parent_key

drugbank key

Details

The following experimental properties are provided:

Property	Description
Water Solubility	The experimentally determined aqueous solubility of the molecule
Molecular Formula	Protein formula of Biotech drugs
Molecular Weight	Protein weight of Biotech drugs
Melting Point	The experimentally determined temperature at which the drug molecule changes from solid to liquid at atmospheric temperature.
Boiling Point	The experimentally determined temperature at which the drug molecule changes from liquid to gas at atmospheric temperature
Hydrophobicity	The ability of a molecule to repel water rather than absorb or dissolve water
Isoelectric Point	The pH value at which the net electric charge of a molecule is zero
caco2 Permeability	A continuous line of heterogeneous human epithelial colorectal adenocarcinoma cells, CAC02 cells are employed as a model of human intestinal absorption of various drugs and compounds. CAC02 cell permeability is ultimately an assay to measure drug absorption
pKa	The experimentally determined pka value of the molecule.
logP	The experimentally determined partition coefficient (LogP) based on the ratio of solubility of the molecule in 1-octanol compared to water
logS	The intrinsic solubility of a given compound is the concentration in equilibrium with its solid phase that dissolves into solution, given as the natural logarithm (LogS) of the concentration.
Radioactivity	The property to spontaneously emit particles (alpha, beta, neutron) or radiation (gamma, K capture), or both at the same time, from the decay of certain nuclides

Source

Drugbank Documentation