Experimental_Properties_Drug {covid19dbcand} | R Documentation |
Drug Experimental Properties
Description
Drug properties that have been experimentally proven. Each drug may have one or more experimental property.
Usage
Experimental_Properties_Drug
Format
a tibble with 4 variables:
- kind
Name of the property
- value
Drug properties that have been experimentally proven
- source
Reference to the source of this experimental data
- parent_key
drugbank key
Details
The following experimental properties are provided:
Property | Description |
Water Solubility | The experimentally determined aqueous solubility of the molecule |
Molecular Formula | Protein formula of Biotech drugs |
Molecular Weight | Protein weight of Biotech drugs |
Melting Point | The experimentally determined temperature at which the drug molecule changes from solid to liquid at atmospheric temperature. |
Boiling Point | The experimentally determined temperature at which the drug molecule changes from liquid to gas at atmospheric temperature |
Hydrophobicity | The ability of a molecule to repel water rather than absorb or dissolve water |
Isoelectric Point | The pH value at which the net electric charge of a molecule is zero |
caco2 Permeability | A continuous line of heterogeneous human epithelial colorectal adenocarcinoma cells, CAC02 cells are employed as a model of human intestinal absorption of various drugs and compounds. CAC02 cell permeability is ultimately an assay to measure drug absorption |
pKa | The experimentally determined pka value of the molecule. |
logP | The experimentally determined partition coefficient (LogP) based on the ratio of solubility of the molecule in 1-octanol compared to water |
logS | The intrinsic solubility of a given compound is the concentration in equilibrium with its solid phase that dissolves into solution, given as the natural logarithm (LogS) of the concentration. |
Radioactivity | The property to spontaneously emit particles (alpha, beta, neutron) or radiation (gamma, K capture), or both at the same time, from the decay of certain nuclides |
Source
[Package covid19dbcand version 0.1.1 Index]