| signature {cosmicsig} | R Documentation |
Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.3 - June 2022)
Description
Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.3 - June 2022)
Usage
signature
Format
A list with the following elements:
GRCh37: Homo sapiens (human) genome assembly GRCh37.
GRCh38: Homo sapiens (human) genome assembly GRCh38.
mm9: Mus musculus (house mouse) genome assembly mm9.
mm10: Mus musculus (house mouse) genome assembly mm10.
rn6: Rattus norvegicus (Norway rat) genome assembly rn6.
Each element contains the sub elements:
SBS96: Strand-agnostic single-base substitutions in trinucleotide context.
DBS78: Strand-agnostic doublet-base substitutions.
Element GRCh37 contains the additional sub elements:
ID: Strand-agnostic indels (short insertions and deletions).
Remark
The signatures are all genome signatures.
See CatalogRowOrder
in package ICAMS for the classification of mutation types.
Source
https://cancer.sanger.ac.uk/signatures/.
Examples
sbs96_sig <- signature$GRCh37$SBS96