COSMIC_v3.2 {cosmicsig}

Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.2 - March 2021)

Description

Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.2 - March 2021)

Usage

COSMIC_v3.2

Format

A list with two elements, signature and etiology.

• signature is a list with the same structure as signature.

• etiology is a list with the same structure as etiology.

Note

SBS10c, SBS10d, SBS91, SBS92, SBS93, SBS94 (total 6) new SBS signatures were added in COSMIC v3.2. See the news from COSMIC release for more details https://cosmic-blog.sanger.ac.uk/cosmic-mutational-signatures-release-v3-2/

Remark

The signatures are all genome signatures.
See CatalogRowOrder in package ICAMS for the classification of mutation types.

Source

https://cancer.sanger.ac.uk/signatures/.

Examples

sbs96_sig_v3.2 <- COSMIC_v3.2$signature$GRCh37$SBS96