ocarcinoma {coin} | R Documentation |
Ovarian Carcinoma
Description
Survival times of 35 women suffering from ovarian carcinoma at stadium II and IIA.
Usage
ocarcinoma
Format
A data frame with 35 observations on 3 variables.
time
-
time (days).
stadium
-
a factor with levels
"II"
and"IIA"
. event
-
status indicator for
time
:FALSE
for right-censored observations andTRUE
otherwise.
Details
Data from Fleming et al. (1980) and Fleming, Green and Harrington (1984). Reanalysed in Schumacher and Schulgen (2002).
Source
Fleming, T. R., Green, S. J. and Harrington, D. P. (1984). Considerations for monitoring and evaluating treatment effects in clinical trials. Controlled Clinical Trials 5(1), 55–66. doi:10.1016/0197-2456(84)90150-8
Fleming, T. R., O'Fallon, J. R., O'Brien, P. C. and Harrington, D. P. (1980). Modified Kolmogorov-Smirnov test procedures with application to arbitrarily right-censored data. Biometrics 36(4), 607–625. doi:10.2307/2556114
References
Schumacher, M. and Schulgen, G. (2002). Methodik Klinischer Studien: Methodische Grundlagen der Planung, Durchführung und Auswertung. Heidelberg: Springer.
Examples
## Exact logrank test
lt <- logrank_test(Surv(time, event) ~ stadium, data = ocarcinoma,
distribution = "exact")
## Test statistic
statistic(lt)
## P-value
pvalue(lt)