multi_omics_sd {coglasso}R Documentation

Multi-omics dataset of sleep deprivation in mouse

Description

A dataset containing transcript and metabolite values analysed in Albanese et al. 2023, subset of the multi-omics data set published in Jan, M., Gobet, N., Diessler, S. et al. A multi-omics digital research object for the genetics of sleep regulation. Sci Data 6, 258 (2019).

multi_omics_sd_small is a smaller version, limited to the transcript Cirbp and the transcripts and metabolites belonging to its neighborhood as described in Albanese et al. 2023

multi_omics_sd_micro is a minimal version with Cirbp and a selection of its neighborhood.

Usage

multi_omics_sd

multi_omics_sd_small

multi_omics_sd_micro

Format

multi_omics_sd

A data frame with 30 rows and 238 variables (162 transcripts and 76 metabolites):

Plin4 to Tfrc

log2 CPM values of 162 transcripts in mouse cortex under sleep deprivation (-4.52–10.46)

Ala to SM C24:1

abundance values of 76 metabolites (0.02–1112.67)

multi_omics_sd_small

A data frame with 30 rows and 19 variables (14 transcripts and 5 metabolites)

Cirbp to Stip1

log2 CPM values of 14 transcripts in mouse cortex under sleep deprivation (4.24–9.31)

Phe to PC ae C32:2

Abundance values of 5 metabolites (0.17–145.33)

multi_omics_sd_micro

A data frame with 30 rows and 6 variables (4 transcripts and 2 metabolites)

Cirbp to Dnajb11

log2 CPM values of 4 transcripts in mouse cortex under sleep deprivation (4.78–9.31)

Trp to PC aa C36:3

Abundance values of 2 metabolites (58.80–145.33)

Source

Jan, M., Gobet, N., Diessler, S. et al. A multi-omics digital research object for the genetics of sleep regulation. Sci Data 6, 258 (2019) doi:10.1038/s41597-019-0171-x

Figshare folder of the original manuscript: https://figshare.com/articles/dataset/Input_data_for_systems_genetics_of_sleep_regulation/7797434


[Package coglasso version 1.0.2 Index]