rfactor {cliot}

R Factor for Liver Injury

Description

Using alanine aminotransferase and alkaline phosphatase calculate an index that can distinguish between hepatocellulal, cholestatic, or a combination of both in patients presenting with acute liver injury. Recommended for use in risk stratification and diagnosis by the American College of Gastroenterology.

Usage

rfactor(alt, alp)

Arguments

alt

Numeric value of alanine aminotransferase (U/L).

alp

Numeric value of alkaline phosphatase (U/L).

Value

A numeric value/vector with predicted cause of liver injury.

References

Bénichou C. Criteria of drug-induced liver disorders. Report of an international consensus meeting. J Hepatol. 1990;11(2):272-6. Chalasani NP, Hayashi PH, Bonkovsky HL, et al. ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury. Am J Gastroenterol. 2014;109(7):950-66.

Examples

# The function is defined as
rfactor(40, 50)