Clinical Trial Design and Data Analysis Functions

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Documentation for package ‘clinfun’ version 1.1.5

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

aucVardiTest	Two-Sample Tests for Growth Curves under Dependent Right Censoring
bdrycross.prob	Stopping rule for toxicity/futility monitoring
calogrank	Survival curves analysis of covariance
coxphCPE	Concordance Probability Estimate for Cox model
coxphERR	Heller Explained Relative Risk
coxphQuantile	Survival time quantile as a function of covariate
CPS.ssize	Trial Designs Based On Fisher's Exact Test
deltaAUC	Comparing the AUC from ROC curves from nested binary regression
fe.mdor	Trial Designs Based On Fisher's Exact Test
fe.power	Trial Designs Based On Fisher's Exact Test
fe.ssize	Trial Designs Based On Fisher's Exact Test
fedesign	Trial Designs Based On Fisher's Exact Test
futilbdry	Stopping rule for toxicity/futility monitoring
gsdesign	Group Sequential Designs
gsdesign.binomial	Group Sequential Designs
gsdesign.normal	Group Sequential Designs
gsdesign.survival	Group Sequential Designs
ipmn	Comparing the AUC from ROC curves from nested binary regression
jonckheere.test	Exact/permutation version of Jonckheere-Terpstra test
ktau	Kendall's tau-b estimate
lines.roc.curve	Empirical ROC curve
mdrr	Trial Designs Based On Fisher's Exact Test
oc.twostage.bdry	Two-stage boundary operating characteristics
or2pcase	Trial Designs Based On Fisher's Exact Test
permlogrank	Permutation version of survdiff
ph2simon	Simon's 2-stage Phase II design
ph2single	Exact single stage Phase II design
plot.ph2simon	Simon's 2-stage Phase II design
plot.roc.curve	Empirical ROC curve
plot.roc.perm.test	Permutation test to compare ROC curve
power.ladesign	Power of k-sample rank test under Lehmann alternative
print.futilbdry	Stopping rule for toxicity/futility monitoring
print.ladesign	Power of k-sample rank test under Lehmann alternative
print.ph2simon	Simon's 2-stage Phase II design
print.roc.area.test	Nonparametric area under the ROC curve
print.roc.curve	Empirical ROC curve
print.roc.perm.test	Permutation test to compare ROC curve
print.toxbdry	Stopping rule for toxicity/futility monitoring
pselect	Probability of selection under pick the winner rule
roc.area.test	Nonparametric area under the ROC curve
roc.curve	Empirical ROC curve
roc.perm.test	Permutation test to compare ROC curve
ROCanalysis	Functions to plot and compare ROC curves.
rocanalysis	Functions to plot and compare ROC curves.
toxbdry	Stopping rule for toxicity/futility monitoring
twostage.admissible	Admissible design options between Minimax and Optimal
twostage.inference	Inference following a two-stage design for binary response