| gardner2010 {chlorpromazineR} | R Documentation |
Chlorpromazine equivalent key from Gardner et al. 2010 data
Description
A list of antipsychotics and their chlorpromazine equivalent doses, generated from the following file included with the package: system.file("extdata", "gardner2010.csv", package="chlorpromazineR").
Usage
gardner2010
Format
A named list of 3 named lists (1 for each route) and each sub-list contains the conversion factors for each antipsychotic. The 3 top-level lists are named 'oral', 'sai', and 'lai' (route), and the lists they contain have names corresponding to the antipsychotic, e.g. 'olanzapine'.
Details
The SAI data is not included in this key, because the original study did not specify a conversion factor from chlorpromazine LAI to oral. The alternative key gardner2010_withsai can be used, which includes the SAI data, but the chlorpromazine equivalent doses produced are equivalent to chlorpromazine SAI not chlorpromazine oral. They could be manually converted (e.g. by multiplying the SAI doses by 3 per equivalence noted by Davis 1974 <https://doi.org/10.1016/0022-3956(74)90071-5>)
Source
Gardner, D. M., Murphy, A. L., O’Donnell, H., Centorrino, F., & Baldessarini, R. J. (2010). International consensus study of antipsychotic dosing. The American Journal of Psychiatry, 167(6), 686–693. <https://doi.org/10.1176/appi.ajp.2009.09060802>