| A10_vSMC_volume_data {cellVolumeDist} | R Documentation |
Volume distribution data for A10 vSMC cell cultures
Description
Volume distribution data for A10 vSMC cell cultures with the DNA polymerase inhibitor aphidicolin added at 0nM, 50nM and 100nM concentration.
Usage
data(A10_vSMC_volume_data)Format
The data is formated as 12 numeric vectors of length 257 representing
cell volume (\mu m^3) distributions, namely
"Aph0\_a",
"Aph0\_b",
"Aph0\_c",
"Aph0\_d",
"Aph50\_a",
"Aph50\_b",
"Aph50\_c",
"Aph50\_d",
"Aph100\_a",
"Aph100\_b",
"Aph100\_c", and
"Aph100\_d". The name of the object indicates the concentration of
aphidicolin present in nM (e.g., "Aph0\_a" represents measurements in the
presence of 0nM of aphidicolin). Four repetitions of measurements at
each of the three concentrations are included.
The estimated cell cycle time (h) for each volume
distribution
dataset is indicated in the numeric objects
"tAph0\_a",
"tAph0\_b",
"tAph0\_c",
"tAph0\_d",
"tAph50\_a",
"tAph50\_b",
"tAph50\_c",
"tAph50\_d", "tAph100\_a", "tAph100\_b", "tAph100\_c", and "tAph100\_d".
The object "volumes\_A10\_vSMC" is a numeric vector representing the volumes
(\mu m^3) associated with all of the distributions.
Source
The measurement protocol is described in the paper in the references.
References
Halter M, Elliott JT, Hubbard JB, Tona A, Plant AL (2009), "Cell Volume Distributions Reveal Cell Growth Rates and Division Times", Journal of Theoretical Biology, Vol 257, pp 124 - 130, DOI: 10.1016/j.jtbi.2008.10.031.
Examples
data(A10_vSMC_volume_data)
plot(volumes_A10_vSMC, Aph100_b,
main=expression(paste("Distribution of cell volumes (",mu, m^3,")",sep="")),
type="b", pch=20, ylab="frequency",
xlab=expression(paste("volume (",mu, m^3,")", sep="")))