tide.ci.zero.rho {ccmm}R Documentation

Bootstrap samples of TIDE with zero correlation

Description

Generate bootstrap samples of the total indirect effect (TIDE) when the correlation coefficient is zero

Usage

tide.ci.zero.rho(y, M, tr, x = NULL, w = NULL, n.boot=2000)

Arguments

y

Vector of continuous outcomes

M

Matrix of compositional data

tr

Vector of continuous or binary treatments

x

Matrix of covariates

w

Vector of weights on samples

n.boot

Number of bootstrap samples

Value

bootstrap samples of TIDE

Author(s)

Michael B. Sohn

Maintainer: Michael B. Sohn <msohn@mail.med.upenn.edu>

References

Sohn, M.B. and Li, H. (2017). Compositional Mediation Analysis for Microbiome Studies (AOAS: In revision)

Examples

# Load test data
data(ccmm_test_data);
outcome <- ccmm_test_data[,1];
treatment <- ccmm_test_data[,2];
mediators <- as.matrix(ccmm_test_data[,3:22]);
covariates <- as.matrix(ccmm_test_data[,23:24]);

cisa <- tide.ci.zero.rho(outcome, mediators, treatment, covariates, n.boot=200)

[Package ccmm version 1.0 Index]