| es1plates {braidrm} | R Documentation |
Plate Information from Ewings-Sarcoma Experiments
Description
These data frames describe the compounds used in each of plates tested in a series of cytotoxicity experiments on cell-lines from the pediatric cancer Ewings' sarcoma. Data frames describe plates from several different experiments or sets of experiments:
- es1plates
Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the ES1 cell line.
- es1extplates
Follow up experiments combining BMN 673 and SN-38 with several additional mechanistic classes in the ES1 cell line.
- es8plates
Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the ES8 cell line.
- es8extplates
Follow up experiments combining BMN 673 and SN-38 with several additional mechanistic classes in the ES8 cell line.
- ew8plates
Experiment combining three PARP inhibitors with standard-of-care DNA damaging agents in the EW8 cell line.
Usage
data(ewings)Format
Data frames containing the following columns:
- plate
The number of a plate run in a particular experiment
- compound1
The compound drugged in decreasing concentration across the plate (DMSO if none)
- compound2
The compound drugged in decreasing concentration down the plate (DMSO if none)
- posmean
The average base-10 logarithm of CellTiter-Glo intensity in positive control wells on the plate, normalized to intensity in negative control wells on the same plate
- date
The date on which the experiment using that plate was run