getOC {bossR}

Select Optimal cutoff for a biomarker

Description

Given a set of data including survival time ,censor status and Biomarker values, return the Optimal cutoff for the biomarker.

Usage

getOC(data, cutoff, type = 2)

Arguments

data

A data frame which contains 3 columns for cox regression : survival time, censor status, Biomarker values. 2 columns for linear regression : Y, X.

cutoff

Numeric vector of candidate cutoffs.

type

A number; if =1, will perform linear regression;if =2(default) will perform cox regerssion.

Value

Optimal cutoff for the biomarker, the FWER of the model

References

BOSS - Biomarker Optimal Segmentation System

Examples

cutoff=c(56,112,167,223,278,334,389,445)
    data(myGene)
    getOC(data=myGene,cutoff)