bdribs.sensitivity {bdribs}

sensitivity plot - plot of range of posterior probability corresponding to a range of background rate

Description

plot of range of posterior probability corresponding to a range of background rate

Usage

bdribs.sensitivity(Y = 5:9, pyr = 800, k = 1, tol = 1.2, bg.evnt = 18,
  bg.pyr = 4000, bg.ci.coef = 0.9, bg.rng = NULL, add.mid = FALSE, ...)

Arguments

Y

range on number of AESI events for which sensitivity range to be drawn (default = 5:9)

pyr

total patient-year exposure where AESI events occurred (default =800)

k

allocation ratio (T:C) (default =1)

tol

clinically meaningful relative risk (default =1.2)

bg.evnt

background (historical) number of events in the control group (default =18)

bg.pyr

background (historical) patient-year exposure in the control group (default =4000)

bg.ci.coef

range of background rate estimate to be obtained from bg.ci.coef*100% CI (default =0.9); takes any value between 0.5 and 0.999.

bg.rng

range of background rate - if specified then bg.evnt, bg.pyr, and bg.ci.coef will be ignored (default =NULL)

add.mid

indicator variable to plot P(r>tol | Y, pyr) under inf.type=2 - requires related parameters to be supplied (default =F)

...

to supply remaining parameters of bdribs call (other than y, pyr, k, bg.events, bg.pyr) for bdribs call when supplied will override the default values

Value

returns a plot of P(r>tol | Y, pyr) over the range of background rate

Examples

## Sample calls
     #run 1: The sensitivity plot
     bdribs.sensitivity(Y=5:9,pyr=800,k=1, tol=1.2, bg.evnt=18, bg.pyr=4000,bg.ci.coef=0.90)
     #run 2: The sensitivity plot
     bdribs.sensitivity(Y=5:9,pyr=800,k=1, tol=1.2, bg.evnt=18, bg.pyr=4000,bg.ci.coef=0.90,
     add.mid=TRUE)
     #run 3: Using bg.rng parameter
     bdribs.sensitivity(Y=5:9,pyr=800,k=1, tol=1.2, bg.rng = c(0.0030, 0.0045, 0.0065))