cgd {bayesSurv}

Chronic Granulomatous Disease data

Description

Dataset from Fleming and Harrington (1991).

Data from a multicenter placebo-controlled randomized trial of gamma inferon in patients with chronic granulomatous disease (CGD). 128 patients were randomized to either gamma inferon (n=63) or placebo (n=65). For each patient the times from study entry to initial and any recurrent serious infections are available. There is a minimum of one and a maximum of eight (recurrent) infection times per patient, with a total of 203 records.

Usage

data(cgd)

Format

a~data frame with 203 rows and 17 columns. There are the following variables contained in the data frame.

hospit

code of the hospital

ID

case identification number

RDT

date randomization onto study (mmddyy)

IDT

date of onset of serious infection, or date the patient was taken off the study (mmddyy)

trtmt

treatment code, 1 = rIFN-gamma, 2 = placebo

inherit

pattern of inheritance, 1 = X-linked, 2 = autosomal recessive

age

age in years

height

height of the patient in cm

weight

weight of the patient in kg

cortico

using corticosteroids at time of study entry, 1 = yes, 2 = no

prophy

using prophylatic antibiotics at time of study entry, 1 = yes, 2 = no

gender

1 = male, 2 = female

hcat

hospital category, 1 = US-NIH, 2 = US-other, 2 = Europe - Amsterdam, 4 = Europe - other

T1

elapsed time (in days) from randomization (from sequence = 1 record) to diagnosis of a serious infection or, if a censored observation, elapsed time from randomization to censoring date; computed as IDT - RDT (from sequence = 1 record)

T2

0, for sequence = 1 record, if sequence > 1, T2 = T1(from previous record) + 1

event

censoring indicator, 1 = non-censored observation, 2 = censored observation

sequence

sequence number, for each patient, the infection recods are in sequence number order

Source

Appendix D.2 of Fleming and Harrington (1991).

References

Fleming, T. R. and Harrington, D. P. (1991). Counting Processes and Survival Analysis. New York: John Wiley and Sons.