appnn {appnn}

Prediction of the amyloidogenicity propensity for polypeptide sequences.

Description

This function predicts the amyloidfogenicity propensity of polypeptide sequences through the amyloid propensity prediction neural network (APPNN).

Usage

## Default S3 method:
appnn(sequences)

Arguments

sequences

vector of sequences to submit to amyloidogenicity propension prediction neural network

Value

A list containing the amyloidogenicity propensity predictions for the polypeptides queried.

overall

The overall amyloidogenicity propensity prediction value for the sequence

aminoacids

The amyloidogenicity propensity prediction value per amino acid

hotspots

A list of the amyloidogenic hotspots predicted in the sequence, limited by the first and last amino acid

Author(s)

Carlos Família, Sarah R. Dennison, Alexandre Quintas, David A. Phoenix

Examples

sequences <- c('STVIIE','KKSSTT','KYSTVI')
predictions <- appnn(sequences)