compute_amanida {amanida} | R Documentation |

`compute_amanida`

Combines for the same entry or metabolite the statistical values of p-value and fold-change. Also is computed a vote-counting for each compound.

compute_amanida(datafile)

`datafile` |
data imported using amanida_read function |

Entries corresponding to metabolites are divided by trend and then combined as follows:

P-values are combined using Fisher method weighted by N and chi-squared distribution

Fold-change are combined by weighted mean

Vote-counting is computed without trend division. Punctuation of entries is based on trend, up-regulation gives 1, down-regulation give -1 and equal behavior gives 0. Total sum is divided then by the total number of entries on each compound.

METAtable S4 object with p-value combined, fold-change combined and vote-counting for each compound

data("sample_data") compute_amanida(sample_data)

[Package *amanida* version 0.0.8 Index]