compare_cohorts {allMT}

R Documentation

Plot summarized maintenance therapy (MT) data to compare two or more cohorts

Description

Create an integrated summary graph facetted (by cohort). Graph illustrates weighted mean absolute neutrophil count (ANC) and dose information for each patient.

Usage

compare_cohorts(
  input_files_path,
  unit,
  anc_range,
  dose_intensity_threshold,
  method,
  intervention_date,
  group_data_path
)

Arguments

input_files_path	Path to folder with MT csv files (in quotes)
unit	Choose either "million" or "billion". "million" = million cells/L (x10^{6} cells/L or cells/\mul) "billion" = billion cells/L (x10^{9} cells/L or x10^{3} cells/\mul)
anc_range	Vector with lower and upper thresholds of absolute neutrophil count target range: (c(lower threshold, upper threshold)) Ensure units of anc_range and patient data (unit) match.
dose_intensity_threshold	numeric value of reference drug dose intensity (%).
method	Choose from "M1" or "M2". "M1" = Comparison of cohorts that started MT therapy before or after a particular date of intervention (intervention_date). "M2" = Comparison of MT therapy between pre-determined groups.
intervention_date	Only applicable if method = "M1". Provide date in yyyy-mm-dd format (in quotes)
group_data_path	Only applicable for method = "M2". Path to EXCEL FILE containing "group" information. Ensure "ID" and "Group" columns are present.

Value

Comparative summary graph

Note

• If more than one chort need to be compared then only "M2" method is applicable

See Also

summarize_cohortMT()

Examples

cohort_path = paste0(system.file("extdata/processed_data/", package = "allMT"), "/")
compare_cohorts(input_files_path = cohort_path,
        method = "M1", intervention_date = "2020-12-01",
        unit = "billion", anc_range = c(0.75, 1.5), dose_intensity_threshold = 100)


group_path = system.file("extdata/grouped_data/group_data.xlsx", package = "allMT")
compare_cohorts(input_files_path = cohort_path,
       method = "M2", group_data_path = group_path,
       unit = "billion", anc_range = c(0.75, 1.5), dose_intensity_threshold = 80)

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