| YPInterimTesting-package {YPInterimTesting} | R Documentation |
Interim Monitoring Using Adaptively Weighted Log-rank Test in Clinical Trials
Description
This package provides monitoring boundary for interim testing using the adaptively weighted log-rank test developed by Yang and Prentice (2010). It is shown in Yang (2018) that the adaptively weighted log-rank test is asymptotically fully efficient when the limiting censoring distributions in two groups are equal. For a given spending function, the main function of the package ypinterim provides stopping boundaries at the interim looks, along with nominal p-values. The object being returned by the function ypinterim can be formatted to a table using the function summary.
Details
| Package: | YPInterimTesting |
| Type: | Package |
| Version: | 1.0.0 |
| Date: | 2018-10-31 |
| License: | GPL (>= 3) |
Author(s)
Daewoo Pak and Song Yang
References
Yang, S. (2018). Interim monitoring using the adaptively weighted log-rank test in clinical trials for survival outcomes. Statistics in Medicine. <doi:10.1002/sim.7958>
Yang, S., & Prentice, R. (2010). Improved logrank-type tests for survival data using adaptive weights. Biometrics, 66(1), 30-38.