getV {VCA} | R Documentation |
Determine V-Matrix for a 'VCA' Object
Description
Determine the estimated variance-covariance matrix of observations .
Usage
getV(obj)
Arguments
obj |
(VCA) object |
Details
A linear mixed model can be written as , where
is the column
vector of observations,
and
are design matrices assigning fixed (
),
respectively, random (
) effects to observations, and
is the column vector of
residual errors.
The variance-covariance matrix of
is equal to
, where
is the variance-covariance matrix of
and
is the variance-covariance matrix of
.
Here,
is assumed to be a diagonal matrix, i.e. all random effects
are mutually independent
(uncorrelated).
Value
(VCA) object with additional elements in the 'Matrices' element, including matrix .
Author(s)
Andre Schuetzenmeister andre.schuetzenmeister@roche.com
[Package VCA version 1.5.1 Index]