getL {VCA}R Documentation

Construct Linear Contrast Matrix for Hypothesis Tests

Description

Function constructs coefficient/contrast matrices from a string-representation of linear hypotheses.

Usage

getL(obj, s, what = c("fixef", "lsmeans"))

Arguments

obj

(VCA) object

s

(character) string or vector of strings, denoting one or multiple linear contrasts

what

(character) string specifying whether to construct contrast matrices of fixed effects ("fixed") or LS Means ("lsmeans"), abbreviations are allowed.

Details

Function constructs matrices expressing custom linear hypotheses of fixed effects or LS Means. The user has to specify a string denoting this contrast which is then transformed into a coefficient/contrast matrix. This string may contain names of fixed effects belonging to same same fixed term, numeric coefficients and mathematical operators "+" and "-" (see examples).

Value

(matrix) representing one linear hypothesis of fixed effects or LS Means per row

Author(s)

Andre Schuetzenmeister andre.schuetzenmeister@roche.com

Examples

## Not run: 
data(dataEP05A2_2)
fit <- anovaMM(y~day/(run), dataEP05A2_2)
L <- getL(fit, c("day1-day2", "day5-day10"), what="fixef")
L
test.fixef(fit, L=L)

# another custom hypothesis
L2 <- getL(fit, "0.25*day1+0.25*day2+0.5*day3-0.5*day4-0.5*day5")
L2

# more complex model
data(VCAdata1)
dataS2 <- VCAdata1[VCAdata1$sample==2,]
fit.S2 <- anovaMM(y~(lot+device)/day/(run), dataS2)
L3 <- getL(fit.S2, c("lot1-lot2", "lot1:device3:day19-lot1:device3:day20", 
"lot1:device1:day1-lot1:device1:day2"))
L3
test.fixef(fit.S2, L3)

## End(Not run)

[Package VCA version 1.5.1 Index]