hpa.data {TPACData}

Gene expression data for normal human tissues from the Human Protein Atlas (HPA). This data was specially processed by the HPA group as FPKM values (file "HPA.normal.FPKM.GDCpipeline.csv") using a pipeline similar to that employed by GDC for the TCGA RNA-seq data.

Description

A data.table with 1,088,694 rows and 4 columns (Gene, Tissue, FPKM, TissueSpecificity):

• Gene: Ensembl gene ID

• Tissue: Human tissue type

• FPKM: Mean expression of that gene in units FPKM+1

• TissueSpecificity: The fold-change in expression between mean expression in that tissue and mean in all 18 tissues.

Usage

hpa.data

Format

A data.table with 1,088,694 rows and 4 columns (Gene, Tissue, FPKM, TissueSpecificity)

Source

Human Protein Atlas

References

• Ulhen et al. (2017). A pathology atlas of the human cancer transcriptome. Science. doi: 10.1126/science.aan2507