est.c.hat {TEAM}

Estimate threshold function

Description

Estimate threshold to control FDR in multiple testing procedure

Usage

est.c.hat(l, n, theta0, x.l, c.hats, alpha, m.l)

Arguments

l

Layer

n

Number of pooled case and control observations in each layer 1 bin

theta0

Nominal boundary level for binomial parameter at layer 1

x.l

Vector of case counts in each bin

c.hats

Previous c.hats calculated from layers 1 to l-1

alpha

Nominal FDR level

m.l

Number of leaf hypotheses at layer l