ConvertWeibull {SurvRegCensCov} | R Documentation |
Transformation of survreg output for the Weibull distribution
Description
Transforms output from survreg
using the Weibull distribution to a more natural parameterization. See details and the vignette for more information.
Usage
ConvertWeibull(model, conf.level = 0.95)
Arguments
model |
A |
conf.level |
Confidence level used to produce two-sided |
Details
The survreg
function fits a Weibull accelerated failure time model of the form
\log t = \mu + \alpha^T Z + \sigma W,
where Z
is a matrix of covariates, and W
has the extreme value distribution, \mu
is the intercept,
\alpha
is a vector of parameters for each of the covariates, and \sigma
is the scale. The usual
parameterization of the model, however, is defined by hazard function
h(t|Z) = \gamma \lambda t^{\gamma - 1} \exp(\beta^T Z).
The transformation is as follows: \gamma = 1/\sigma
, \lambda = \exp(-\mu/\sigma)
, and
\beta=-\alpha/\sigma
, and estimates of the standard errors can be found using the delta method.
The Weibull distribution has the advantage of having two separate interpretations. The first, via proportional hazards, leads to a hazard ratio, defined by \exp \beta
. The second, of accelerated failure times, leads to an event time ratio (also known as an acceleration factor), defined by \exp (-\beta/\gamma)
.
Further details regarding the transformations of the parameters and their standard errors can be found in Klein and
Moeschberger (2003, Chapter 12). An explanation of event time ratios for the accelerated failure time interpretation of the model can be found in Carroll (2003). A general overview can be found in the vignette("weibull")
of this package.
Value
vars |
A matrix containing the values of the transformed parameters and their standard errors |
HR |
A matrix containing the hazard ratios for the covariates, and |
ETR |
A matrix containing the event time ratios for the covariates, and |
Author(s)
Sarah R. Haile, Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich, sarah.haile@uzh.ch
References
Carroll, K. (2003). On the use and utility of the Weibull model in the analysis of survival data. Controlled Clinical Trials, 24, 682–701.
Klein, J. and Moeschberger, M. (2003). Survival analysis: techniques for censored and truncated data. 2nd edition, Springer.
See Also
This function is used by WeibullReg
.
Examples
data(larynx)
ConvertWeibull(survreg(Surv(time, death) ~ stage + age, larynx), conf.level = 0.95)