delta.calculate {SurrogateRank}

Calculates the rank-based test statistic for Y and S and the difference, delta

Description

Calculates the rank-based test statistic for Y and the rank-based test statistic for S and the difference, delta, along with corresponding standard error estimates

Usage

delta.calculate(full.data = NULL, yone = NULL, yzero = NULL, sone = NULL, szero = NULL)

Arguments

full.data

either full.data or yone, yzero, sone, szero must be supplied; if full data is supplied it must be in the following format: one observation per row, Y is in the first column, S is in the second column, treatment group (0 or 1) is in the third column.

yone

primary outcome, Y, in group 1

yzero

primary outcome, Y, in group 0

sone

surrogate marker, S, in group 1

szero

surrogate marker, S, in group 0

Value

u.y

rank-based test statistic for Y

u.s

rank-based test statistic for S

delta

difference, u.y-u.s

sd.u.y

standard error estimate of u.y

sd.u.s

standard error estimate of u.s

sd.delta

standard error estimate of delta

Author(s)

Layla Parast

Examples

data(example.data)
delta.calculate(yone = example.data$y1, yzero = example.data$y0, sone = example.data$s1, 
szero = example.data$s0)