prostate {Surrogate}

The prostate dataset with a continuous surrogate.

Description

This dataset combines the data that were collected in 17 double-blind randomized clinical trials in advanced prostate cancer.

Usage

data("prostate")

Format

A data frame with 412 observations on the following 6 variables.

TRIAL

The ID number of a trial.

TREAT

The treatment indicator, coded as 0=active control and 1=experimental treatment.

PSA

Prostate specific antigen (surrogate endpoint)

SURVTIME

Survival time (the true endpoint).

SURVIND

Censoring indicator for survival time.

PATID

The ID number of a patient.

References

Alonso A, Bigirumurame T, Burzykowski T, Buyse M, Molenberghs G, Muchene L, Perualila NJ, Shkedy Z, Van der Elst W, et al. (2016). Applied surrogate endpoint evaluation methods with SAS and R. CRC Press New York

Examples

data(prostate)
str(prostate)
head(prostate)