colorectal4 {Surrogate} | R Documentation |
The Colorectal dataset with an ordinal surrogate.
Description
This dataset combines the data that were collected in 19 double-blind randomized clinical trials in advanced colorectal cancer.
Usage
data("colorectal4")
Format
A data frame with 3192 observations on the following 7 variables.
trialend
The ID number of a trial.
treatn
The treatment indicator, coded as 0=active control and 1=experimental treatment.
trueind
Censoring indicator for survival time.
surrogend
Categorical ordered tumor response (the candidate surrogate), coded as 1=complete response (CR), 2=partial response (PR), 3=stabled disease (SD) and 4=progressive disease (PD).
patid
The ID number of a patient.
center
The center in which a patient was treated. In this dataset, there was only one center per trial, hence TRIAL=CENTER.
truend
Survival time (the true endpoint).
References
Alonso, A., Bigirumurame, T., Burzykowski, T., Buyse, M., Molenberghs, G., Muchene, L., ... & Van der Elst, W. (2016). Applied surrogate endpoint evaluation methods with SAS and R. CRC Press.
Examples
data(colorectal4)
str(colorectal4)
head(colorectal4)