Schizo_BinCont {Surrogate}

Data of a clinical trial in schizophrenia, with binary and continuous endpoints

Description

These are the data of a clinical trial in schizophrenia. Patients' schizophrenic symptoms were measured using the PANSS, BPRS, and CGI. There were two treatment conditions (risperidone and control).

Usage

data(Schizo)

Format

A data.frame with 446 observations on 9 variables.

Id

The patient ID.

InvestID

The ID of the investigator (psychiatrist) who treated the patient.

Treat

The treatment indicator, coded as -1 = control and 1 = Risperidone.

CGI

The change in the CGI score (= score at the start of the treatment - score at the end of the treatment).

PANSS

The change in the PANSS score.

BPRS

The change in the PANSS score.

PANSS_Bin

The dichotomized PANSS change score, coded as 1 = a reduction of 20% or more in the PANSS score (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.

BPRS_Bin

The dichotomized BPRS change score, coded as 1 = a reduction of 20% or more in the BPRS score (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.

CGI_Bin

The sichtomized change in the CGI score, coded as 1 = a change of more than 3 points on the original scale (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.