Schizo {Surrogate}

Data of five clinical trials in schizophrenia

Description

These are the data of five clinical trials in schizophrenia. A total of 2128 patients were treated by 198 investiagators (psychiatrists). Patients' schizophrenic symptoms were measured using the PANSS, BPRS, and CGI. There were two treatment conditions (risperidone and control).

Usage

data(Schizo)

Format

A data.frame with 2128 observations on 9 variables.

Id

The patient ID.

InvestID

The ID of the investigator (psychiatrist) who treated the patient.

Treat

The treatment indicator, coded as -1 = control and 1 = Risperidone.

CGI

The change in the CGI score (= score at the start of the treatment - score at the end of the treatment).

PANSS

The change in the PANSS score.

BPRS

The change in the PANSS score.

PANSS_Bin

The dichotomized PANSS change score, coded as 1 = a reduction of 20% or more in the PANSS score (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.

BPRS_Bin

The dichotomized BPRS change score, coded as 1 = a reduction of 20% or more in the BPRS score (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.

CGI_Bin

The sichtomized change in the CGI score, coded as 1 = a change of more than 3 points on the original scale (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.