case0501 {Sleuth2} | R Documentation |
Diet Restriction and Longevity
Description
Female mice were randomly assigned to six treatment groups to investigate whether restricting dietary intake increases life expectancy. Diet treatments were:
-
"NP"
—mice ate unlimited amount of nonpurified, standard diet -
"N/N85"
—mice fed normally before and after weaning. After weaning, ration was controlled at 85 kcal/wk -
"N/R50"
—normal diet before weaning and reduced calorie diet (50 kcal/wk) after weaning -
"R/R50"
—reduced calorie diet of 50 kcal/wk both before and after weaning -
"N/R50 lopro"
—normal diet before weaning, restricted diet (50 kcal/wk) after weaning and dietary protein content decreased with advancing age -
"N/R40"
—normal diet before weaning and reduced diet (40 Kcal/wk) after weaning.
Usage
case0501
Format
A data frame with 349 observations on the following 2 variables.
Lifetime
the lifetime of the mice (in months)
Diet
factor variable with six levels—
"NP"
,"N/N85"
,"lopro"
,"N/R50"
,"R/R50"
and"N/R40"
Source
Ramsey, F.L. and Schafer, D.W. (2002). The Statistical Sleuth: A Course in Methods of Data Analysis (2nd ed), Duxbury.
References
Weindruch, R., Walford, R.L., Fligiel, S. and Guthrie D. (1986). The Retardation of Aging in Mice by Dietary Restriction: Longevity, Cancer, Immunity and Lifetime Energy Intake, Journal of Nutrition 116(4):641–54.
Examples
str(case0501)
boxplot(Lifetime~Diet, width=c(rep(.8,6)), data=case0501,
xlab="Diet", ylab="Lifetime in months")
summary(subset(case0501, Diet=="NP", Lifetime))