| Factor {SeqMADE} | R Documentation |
Construction of Variable Factors
Description
A function of constructing the Group variables, Direction variables, and the Count variables.
Usage
Factor(exprs, case, control)
Arguments
exprs |
exprs is a data frame or matrix for two groups or conditions, with rows as variables (genes) and columns as samples. |
case |
case is the sample names in case groups. |
control |
control is the sample names in control groups. |
Details
Two indicator variables Group and Direction corresponding to the different groups and the direction of the gene expression changes in the context of an RNA-Seq experiment, respectively. And in this part, 1 represents that a gene belongs to case group or up-regulated and 0 represents a gene belongs to control group or down-regulated. Besides, Count variables are the expression value in different samples for genes.
Value
Count |
The gene expression count values. |
Group |
The indicator variables represent that whether a gene belongs to case group or not. |
Direction |
The indicator variables represent that a gene is up-regulated or down-regulated. |
Author(s)
Mingli Lei, Jia Xu, Li-Ching Huang, Lily Wang, Jing Li
Examples
data(exprs)
case <- c("A1","A2","A3","A4","A5","A6","A7")
control <- c("B1","B2","B3","B4","B5","B6","B7")
factors <- Factor(exprs, case, control)