Get_EffectiveNumberTest {SKAT}

Estimate the effective number of tests for Bonferroni correction

Description

Estimate the effective number of tests for Bonferroni correction using the minimum achievable p-values (MAP).

Usage

 
 
	Get_EffectiveNumberTest(MAP, alpha=0.05, Is.MidP=TRUE) 


 

Arguments

MAP

a vector of the minimum achievable p-values (MAP).

alpha

a significant level.

Is.MidP

a logical value indicating whether p-values are mid-p-values.

Value

Effective number of test for Bonferroni correction at the level alpha. MAP can be obtained from SKATBinary functions.

Author(s)

Seunggeun Lee

References

Lee, S., Fuchsberger, C., Kim, S., Scott, L. (2015) An efficient resampling method for calibrating single and gene-based rare variant association analysis in case-control studies. Biostatistics, in press.