Scalable Exact Algorithm for Large-Scale Set-Based Gene-Environment Interaction Tests

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Documentation for package ‘SEAGLE’ version 1.0.1

• DESCRIPTION file.
• User guides, package vignettes and other documentation.

Help Pages

applyAt	Function for applying t(A) on the left for REML EM
cosihap	Synthetic haplotype data generated from COSI software
estimate.vc	REML EM Algorithm
makeSimData	Generate synthetic data according to a fixed effects model
prep.SEAGLE	Prepare data for input into SEAGLE function
Rinv.AtG	Function for applying R inverse to AtG in REML EM algorithm
Rinv.u	Function for applying R inverse to u in REML EM algorithm
SEAGLE	Compute score-like test statistic and p-value for GxE test with SEAGLE algorithm
Vinv	Function for applying V inverse in Algorithm 1