conduct.phase2 {SAME}

Function to identify the most promising treatment-biomarker-linked subgroup

Description

This function is used to estimate the effect size of each subgroup and to select the most promising subgroup.

Usage

conduct.phase2(formula, surv, event, data)

Arguments

formula

a formula object, with the combinations of treatment and biomarker term, e.g., formula = "T1:B1+T1:B2+T2:B1+T2:B2"

surv

survival time

event

the status indicator, 0=alive, 1=dead

data

a data.frame in which to interpret the variables named in the formula

Value

conduct.phase2() select the most effective subgroup and returns the estimated hazard ratio.

Examples

conduct.phase2(formula = "T1:B1+T1:B2+T2:B1+T2:B2", surv = "surv",
event = "death", data = "example.1")