crohn {RBesT} | R Documentation |
Crohn's disease.
Description
Data set containing historical information for placebo arm of relevant studies for the treatment of Crohn's disease. The primary outcome is change from baseline in Crohn's Disease Activity Index (CDAI) over a duration of 6 weeks. Standard deviation of change from baseline endpoint is approximately 88.
Usage
crohn
Format
A data frame with 4 rows and 3 variables:
- study
study
- n
study size
- y
mean CDAI change
References
Hueber W. et. al, Gut, 2012, 61(12):1693-1700
Examples
## Setting up dummy sampling for fast execution of example
## Please use 4 chains and 20x more warmup & iter in practice
.user_mc_options <- options(RBesT.MC.warmup=50, RBesT.MC.iter=100,
RBesT.MC.chains=2, RBesT.MC.thin=1)
set.seed(546346)
map_crohn <- gMAP(cbind(y, y.se) ~ 1 | study,
family=gaussian,
data=transform(crohn, y.se=88/sqrt(n)),
weights=n,
tau.dist="HalfNormal", tau.prior=44,
beta.prior=cbind(0,88))
## Recover user set sampling defaults
options(.user_mc_options)
[Package RBesT version 1.7-3 Index]