Power and Sample-Size Distribution of 2-Stage Bioequivalence Studies


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Documentation for package ‘Power2Stage’ version 0.5-4

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final.2stage.in Analysis after second stage of 2-stage 2x2 crossover design based on the Inverse Normal method
final.tsd.in Analysis after second stage of 2-stage 2x2 crossover design based on the Inverse Normal method
interim.2stage.in Interim analysis of first stage data of 2-stage 2x2 crossover designs based on the Inverse Normal method
interim.tsd.in Interim analysis of first stage data of 2-stage 2x2 crossover designs based on the Inverse Normal method
power.2stage Power calculation of adaptive 2-stage BE studies in a 2x2 crossover design
power.2stage.fC Power calculation of adaptive 2-stage BE studies (2x2 crossover) with a futility criterion for the point estimate of T/R or its 90% CI
power.2stage.GS Power calculation for non-adaptive group sequential (2-stage) BE studies
power.2stage.in Power calculation of adaptive 2-stage BE studies with 2x2 crossover design, based on the Inverse Normal method
power.2stage.KM Power calculation of adaptive 2-stage BE studies (2x2 crossover) (variant of power.2stage to obtain the results of Karalis / Macheras)
power.2stage.p Power calculation of adaptive 2-stage BE studies in 2-group parallel designs
power.2stage.pAF Power calculation of adaptive 2-stage BE studies in 2-group parallel designs
power.2stage.ssr Power of 2-stage BE studies in 2x2 crossover designs with interim sample size re-estimation
power.tsd Power calculation of adaptive 2-stage BE studies in a 2x2 crossover design
power.tsd.fC Power calculation of adaptive 2-stage BE studies (2x2 crossover) with a futility criterion for the point estimate of T/R or its 90% CI
power.tsd.GS Power calculation for non-adaptive group sequential (2-stage) BE studies
power.tsd.in Power calculation of adaptive 2-stage BE studies with 2x2 crossover design, based on the Inverse Normal method
power.tsd.KM Power calculation of adaptive 2-stage BE studies (2x2 crossover) (variant of power.2stage to obtain the results of Karalis / Macheras)
power.tsd.p Power calculation of adaptive 2-stage BE studies in 2-group parallel designs
power.tsd.pAF Power calculation of adaptive 2-stage BE studies in 2-group parallel designs
power.tsd.ssr Power of 2-stage BE studies in 2x2 crossover designs with interim sample size re-estimation
sampleN2.TOST Sample size re-estimation of adaptive 2-stage BE studies in 2x2 crossover and parallel designs based on power of TOST