assignPoD |
Assign probability of disease (PoD) |
BlindSampling |
Immunogenicity subset: vaccinated, control, non-diseased |
ClinicalTrial |
Clinical trial: estimation of case-count efficacy |
ClinicalTrialCoverage |
Clinical trial function expanded for usage in simulations when the calculation of coverage probability is needed for three confidence intervals: 80%, 90%, and user-defined |
control |
Dataset containing the information for control subjects |
cppMLE |
Maximum likelihood estimation: cpp |
cppPoD |
Probability of disease calculation |
diseased |
Dataset containing the information for diseased subjects |
EfficacyCI |
PoDBAY efficacy summary: mean, median, confidence intervals |
EfficacyCICoverage |
PoDBAY efficacy summary at three confidence levels |
efficacyComputation |
PoDBAY efficacy equation |
efficacySet |
Estimated PoDBAY efficacies |
efficacySquaredError |
Optimization objective function: efficacy squared error |
estimatedParameters |
Estimated PoD curve parameters |
ExpectedPoD |
Expected probability of disease |
ExtractDiseased |
Diseased subjects extraction |
ExtractNondiseased |
Non-diseased subjects extraction |
fitPoD |
PoD curve: fitting function |
GenerateNondiseased |
Generation of upsampled non-diseased subjects titers |
generatePopulation |
Population class object generation |
getDiseasedCount |
Diseased count |
getDiseasedTiters |
Diseased titers |
getNondiseasedCount |
Non-diseased count |
getNondiseasedTiters |
Non-diseased titers |
getTiters |
Subject level titers |
getUnknown |
Generate unknown |
ImmunogenicitySubset |
Immunogenicity subset |
incorrectInput |
Error message |
incorrectPopulationInput |
Population class error message |
JitterMean |
Population mean jittering |
MLE |
Maximum Likelihood estimation |
nondiseased |
Dataset containing the information for non-diseased subjects |
numToBool |
Numeric to boolean |
PmaxEstimation |
PoD curve paramater, pmax, estimation |
PoD |
Probability of disease calculation |
PoDBAY |
PoDBAY |
PoDBAYEfficacy |
PoDBAY efficacy estimation |
PoDCI |
PoD curve confidence ribbon |
PoDCurvePlot |
PoD curve: plot |
PoDEfficacySquaredError |
Optimization function: finds PoD curve paramaters (et50, slope) |
PoDMLE |
Setup for the maximum likelihood estimation (MLE) |
PoDParamEstimation |
PoD curve parameters estimation |
PoDParamPointEstimation |
PoD curve point estimate |
PoDParams |
PoD curve parameters |
PoDParamsCI |
Confidence intervals of PoD curve parameters |
PoDParamsCICoverage |
Confidence intervals of PoD curve parameters at three confidence levels |
popFun |
Population function |
population |
Population class |
Population-class |
Population class |
popX |
Add noise to population titers |
vaccinated |
Dataset containing the information for vaccinated subjects |
waldCI |
Wald confidence interval estimation |