| hotspot {PlasmaMutationDetector2} | R Documentation |
The package provide a list of known hotspot positions located on the amplicons of the Ion AmpliSeq™ Colon and Lung Cancer Panel v2 as a txt file hotspot.txt which contains a vector/variable —named chrpos (first row)— of chars, of the form chrN:XXXXXXXXX defining genomic positions.
Description
The package provide a list of known hotspot positions located on the amplicons of the Ion AmpliSeq™ Colon and Lung Cancer Panel v2 as a txt file hotspot.txt which contains a vector/variable —named chrpos (first row)— of chars, of the form chrN:XXXXXXXXX defining genomic positions.
Usage
data(hotspot)
Author(s)
N. Pécuchet, P. Laurent-Puig, O. Nordgård and Y. Rozenholc
References
Analysis of base-position error rate of next-generation sequencing to detect tumor mutations in circulating DNA N. Pécuchet, Y. Rozenholc, E. Zonta, D. Pietraz, A. Didelot, P. Combe, L. Gibault, J-B. Bachet, V. Taly, E. Fabre, H. Blons, P. Laurent-Puig in Clinical Chemistry
Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing Kjersti Tjensvoll, Morten Lapin, Bjørnar Gilje, Herish Garresori, Satu Oltedal, Rakel Brendsdal Forthun, Anders Molven, Yves Rozenholc and Oddmund Nordgård in Scientific Reports