EBS {PRANA}

EBS

Description

A function to calculate the adjusted p-value for each gene (Datta and Datta, 2005)

Usage

EBS(pvo, alpha = 0.05, B = 500, h = 1)

Arguments

pvo

An object with p-values estimated from the user-provided expression data

alpha

a level of significance (default is 0.05)

B

size of bootstrapping (default is 500)

h

a bandwidth (default is 1)

Value

A vector of adjusted p-values for each gene.

References

Datta, S and Datta, S (2005). Empirical Bayes screening of many p-values with applications to microarray studies. Bioinformatics, 21(9), 1987-1994