OneComp_Volume_RateConstant {PKconverter}

Convert pharmacokinetic parameters for one compartment model

Description

Calculate pharmacokinetic parameters with volume of distribution (V1) and elimination rate constant (k10)

Usage

OneComp_Volume_RateConstant(V1,k10,
             V1.sd=NA,k10.sd=NA,covar=c(V1k10=0),...)

Arguments

V1

The volume of distribution of compartment 1

k10

elimination rate constant

V1.sd

standard error of V1

k10.sd

standard error of k10

covar

covariances among parameters

...

arguments to be passed to methods

References

http://www.nonmemcourse.com/convert.xls

Examples

OneComp_Volume_RateConstant(V1=8,k10=0.5,V1.sd=0.01,k10.sd=0.002)