OneComp_Volume_Clearance {PKconverter}

Convert pharmacokinetic parameters for one compartment model

Description

Calculate pharmacokinetic parameters with volume of distribution (V1) and clearance (Cl1)

Usage

OneComp_Volume_Clearance(V1,Cl1,V1.sd=NA,Cl1.sd=NA,
        covar=c(V1Cl1=NA),...)

Arguments

V1

The volume of distribution of compartment 1

Cl1

Clearance from compartment 1

V1.sd

standard error of V1

Cl1.sd

standard error of Cl1

covar

covariances among parameters

...

arguments to be passed to methods

References

http://www.nonmemcourse.com/convert.xls

Gabrielsson and Weiner(2006) Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Swedish Academy of Pharmaceutical Sciences.

Examples

OneComp_Volume_Clearance(V1=8,Cl1=4,V1.sd=0.01,Cl1.sd=0.01)