advan_process_infusion_doses {PKPDsim}

Add column RATEALL to ADVAN-style dataset to handle infusions

Description

Function adapted from code from Abuhelwa, Foster, Upton JPET 2015. cleaned up and somewhat optimized. Can potentially be optimized more.

Usage

advan_process_infusion_doses(data)

Arguments

data

ADVAN-style dataset, e.g. created using 'advan_create_data'.

Value

Data frame containing additional RATEALL column.

References

Abuhelwa, A. Y., Foster, D. J. R., Upton, R. N. (2015) ADVAN-style analytical solutions for common pharmacokinetic models. J Pharmacol Toxicol Methods 73:42-8. DOI: 10.1016/j.vascn.2015.03.004