var_sparse_auc {PKNCA} | R Documentation |
Calculate the variance for the AUC of sparsely sampled PK
Description
Equation 7.vii in Nedelman and Jia, 1998 is used for this calculation:
Usage
var_sparse_auc(sparse_pk)
Arguments
sparse_pk |
A sparse_pk object from |
Details
The degrees of freedom are calculated as described in equation 6 of the same paper.
References
Nedelman JR, Jia X. An extension of Satterthwaite’s approximation applied to pharmacokinetics. Journal of Biopharmaceutical Statistics. 1998;8(2):317-328. doi:10.1080/10543409808835241
[Package PKNCA version 0.11.0 Index]