pk.tss.data.prep {PKNCA}

Clean up the time to steady-state parameters and return a data frame for use by the tss calculators.

Description

Clean up the time to steady-state parameters and return a data frame for use by the tss calculators.

Usage

pk.tss.data.prep(
  conc,
  time,
  subject,
  treatment,
  subject.dosing,
  time.dosing,
  options = list(),
  conc.blq = NULL,
  conc.na = NULL,
  check = TRUE,
  ...
)

Arguments

conc

Measured concentrations

time

Time of the measurement of the concentrations

subject

Subject identifiers (used as a random effect in the model)

treatment

Treatment description (if missing, all subjects are assumed to be on the same treatment)

subject.dosing

Subject number for dosing

time.dosing

Time of dosing

options

List of changes to the default PKNCA options (see PKNCA.options())

conc.blq

See clean.conc.blq()

conc.na

See clean.conc.na()

check

Run assert_conc_time()?

...

Discarded inputs to allow generic calls between tss methods.

Value

a data frame with columns for concentration, time, subject, and treatment.