pk.calc.mrt {PKNCA}

Calculate the mean residence time (MRT) for single-dose data or linear multiple-dose data.

Description

Calculate the mean residence time (MRT) for single-dose data or linear multiple-dose data.

Usage

pk.calc.mrt(auc, aumc)

pk.calc.mrt.iv(auc, aumc, duration.dose)

Arguments

auc

the AUC from 0 to infinity or 0 to tau

aumc

the AUMC from 0 to infinity or 0 to tau

duration.dose

The duration of the dose (usually an infusion duration for an IV infusion)

Details

mrt is aumc/auc - duration.dose/2 where duration.dose = 0 for oral administration.

Value

the numeric value of the mean residence time

Functions

• pk.calc.mrt.iv(): MRT for an IV infusion

See Also

pk.calc.mrt.md()