CPI975 {PK}

Plasma levels of CPI975 in rats following a single oral dose

Description

The CPI975 data frame has 60 rows and 4 columns.

Format

This data frame contains the following columns:

conc

a numeric vector giving the measured plasma level (microgram/mL).

time

a numeric vector giving the time since administration (hours).

sex

a factor indicating the gender of the rat.

dose

a numeric vector indicating the dose administred (mg/kg).

Details

Nedelman et al. (1995), Table 2 describes serial sampling design were the plasma levels are measured at 5 time points over 24 hours for 10 rats. The same experiment was repeated with different oral dosages and gender.

Source

Nedelman J. R., Gibiansky E. and Lau D. T. W. (1995). Applying Bailer's method for AUC confidence intervals to sparse sampling. Pharmaceutical Research, 12(1):124-128.